Targeted Radiotherapeutics

Precision in Healing
for Tomorrow's Health

Engineered radiopharmaceuticals that deliver lethal radiation with surgical accuracy — destroying cancer cells while preserving healthy tissue.

The Century-Old Radiation Dilemma

Powerful enough to kill tumors. Too dangerous for healthy cells. Until now.

Radiation Damage
Traditional Radiation: Collateral Damage

Therapies That Act Like
Smart Missiles

Our proprietary platform combines advanced ligand design, optimized chelators, and therapeutic isotopes to create targeted radiopharmaceuticals that deliver lethal radiation only to cancer cells.

One dose. One target. Maximum impact.

Our Precision Technology Stack

Every component engineered for unmatched specificity, stability, and therapeutic power — from ligand to isotope.

Hyper-Selective Ligands

Bind exclusively to tumor-specific receptors with sub-nanomolar affinity for zero off-target effects.

Optimized Chelators

Lock radioisotopes with extreme stability — no leakage, no damage to healthy organs.

Alpha & Beta Emitters

High-LET alpha particles for DNA destruction; beta for deeper tissue penetration.

Biodistribution Control

Rapid clearance from healthy organs, prolonged retention in tumors for maximum efficacy.

Life-Changing Clinical Outcomes

Precision isn't theoretical — it's measurable in lives saved and quality preserved.

95%

Tumor Targeting Accuracy

87%

Reduction in Side Effects

1

Single-Dose Protocol

40%

Pediatric Applications

Development Pipeline

From discovery to clinic — advancing multiple candidates across solid tumors and rare cancers.

ATX-101

mCRPC (Prostate Cancer); PSMA+ Solid Tumors
Pre-IND Underway

ATX-202

Pancreatic and FAP-high Solid Tumors
Optimization

ATX-303

Broad Solid Tumors (EPR-driven uptake)
Discovery / Platform Build

ATX-D101

Patient Selection and Response Tracking (PSMA PET Diagnostic)
Preclinical

ATX-D202

Patient Selection for FAP-targeted Therapy (FAP PET Diagnostic)
Preclinical

The Future of Cancer Therapy Is Here

Join us in redefining what's possible in oncology. Precision. Power. Hope.

Partner With Us

PDE4 Prodrug Platform

A next-generation prodrug strategy engineered to unlock anti-inflammatory potency while eliminating systemic toxicity.

Targeted Activation

The prodrug remains inert in circulation and is selectively activated at disease-relevant tissue microenvironments, ensuring localized efficacy.

Reduced Systemic Toxicity

By avoiding widespread PDE4 inhibition, gastrointestinal and CNS-related side effects are significantly minimized.

Optimized Oral Delivery

Designed for once-daily oral dosing with consistent exposure and predictable pharmacokinetics.

Precision at the Cellular Level

Every component of Ayutara’s platform is engineered to deliver radiation with surgical accuracy — sparing healthy tissue while maximizing tumor kill.

  • Ligand Engineering: Ultra-high affinity ligands bind exclusively to tumor-specific receptors.
  • Chelator Stability: Radioisotopes remain securely bound throughout circulation and decay.
  • Biodistribution Control: Rapid clearance from kidneys and marrow reduces off-target exposure.
  • Clinical Scalability: Designed for GMP manufacturing and global regulatory approval.

Measured Outcomes

Precision delivery results in higher tumor residence time, lower toxicity, and reproducible clinical performance across patient populations.